A RCT of progesterone luteal support for unexplained infertility

A promising new study published in the BJOG Journal (British Journal of Obstetrics and Gynaecology / Royal College of Obstetricians and Gynaecologists) explores the use of vaginal progesterone for couples facing unexplained infertility.

๐Ÿ‘€ Could this pave the way for broader use of vaginal progesterone prior to IVF โ€”especially for those who canโ€™t access IVF due to financial, religious, or logistical barriers? Itโ€™s a compelling question, and the results suggest itโ€™s worth further investigation.

Weโ€™re particularly interested in the planned larger trials, which will build on this studyโ€™s effect size to refine sample sizing. Our team at is reaching out to the researchers to explore whether our patient-centric Callavidยฎ vaginal drug delivery technology could support these next steps.

Exciting possibilities ahead for expanding access to fertility care. ๐Ÿ™

Study link here: https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.18171