A RCT of progesterone luteal support for unexplained infertility

A promising new study published in the BJOG Journal (British Journal of Obstetrics and Gynaecology / Royal College of Obstetricians and Gynaecologists) explores the use of vaginal progesterone for couples facing unexplained infertility.

👀 Could this pave the way for broader use of vaginal progesterone prior to IVF —especially for those who can’t access IVF due to financial, religious, or logistical barriers? It’s a compelling question, and the results suggest it’s worth further investigation.

We’re particularly interested in the planned larger trials, which will build on this study’s effect size to refine sample sizing. Our team at is reaching out to the researchers to explore whether our patient-centric Callavid® vaginal drug delivery technology could support these next steps.

Exciting possibilities ahead for expanding access to fertility care. 🙏

Study link here: https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.18171

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